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Abordagem racional no planejamento de novos tuberculostáticos: inibidores da InhA, enoil-ACP redutase do M. tuberculosis Rational approach in the new antituberculosis agent design: inhibitors of InhA, the enoyl-ACP reductase from Mycobacterium tuberculosis

机译：计划新结核菌的合理方法：Inha抑制剂，结核分枝杆菌enoil-aCp还原酶新抗结核的合理方法

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Carolina Horta Andrade; Kerly Fernanda Mesquita Pasqualoto; Márcio Henrique Zaim; Elizabeth Igne Ferreira;
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1. Radiolabelling and positron emission tomography of PT70, a time-dependent inhibitor of InhA, the Mycobacterium tuberculosis enoyl-ACP reductase [J] . Wang Hui, Liu Li, Lu Yang, Bioorganic and Medicinal Chemistry Letters . 2015,第21期

机译：PT70的放射性标记和正电子发射断层扫描，InhA是时间依赖性抑制剂，结核分枝杆菌烯酰-ACP还原酶
2. Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis [J] . MatviiukT., RodriguezF., SaffonN., European Journal of Medicinal Chemistry: Chimie Therapeutique . 2013,第Null期

机译：3-（9H-芴-9-基）吡咯烷-2,5-二酮衍生物的设计，化学合成及对烯酰-ACP还原酶（InhA）和结核分枝杆菌的生物活性
3. Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach [J] . Chollet Aurelien, Mourey Lionel, Lherbet Christian, Journal of Structural Biology . 2015,第3期

机译：结核分枝杆菌（InhA）的烯酰-ACP还原酶的晶体结构为apo形式，并与通过仿生方法预先形成的异烟肼的活性代谢物复合
4. Lead Optimization and Slow-Onset Inhibition of the Enoyl-ACP Reductase (InhA) from Mycobacterium Tuberculosis. [D] . Pan, Pan. 2012

机译：结核分枝杆菌中Enoyl-ACP还原酶（InhA）的前导优化和缓慢抑制。
5. Radiolabelling and positron emission tomography of PT70 a time-dependent inhibitor of InhA the Mycobacterium tuberculosis enoyl-ACP reductase [O] . Hui Wang, Li Liu, Yang Lu, -1

机译：PT70的放射性标记和正电子发射断层显像InhA是时间依赖性抑制剂结核分枝杆菌烯酰-ACP还原酶
6. Abordagem racional no planejamento de novos tuberculostáticos: inibidores da InhA, enoil-ACP redutase do M. tuberculosis Rational approach in the new antituberculosis agent design: inhibitors of InhA, the enoyl-ACP reductase from Mycobacterium tuberculosis [O] . Carolina Horta Andrade, Kerly Fernanda Mesquita Pasqualoto, Márcio Henrique Zaim, 2008

机译：计划新结核菌的合理方法：Inha抑制剂，结核分枝杆菌enoil-aCp还原酶新抗结核的合理方法

Abordagem racional no planejamento de novos tuberculostáticos: inibidores da InhA, enoil-ACP redutase do M. tuberculosis Rational approach in the new antituberculosis agent design: inhibitors of InhA, the enoyl-ACP reductase from Mycobacterium tuberculosis

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